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I n recent years, US society has seen a sea change in the perception of transgender people, with celebrities such as Caitlyn Jenner and Laverne Cox becoming the recognizable faces of a marginalized population. Transgender rights have also become a mainstream political issue, and the idea that people should be referred to by the names and pronouns they find most fitting—whether or not these designations match those on their birth certificates, or align with the categories of male and female—is gaining acceptance. Yet a biological understanding of the contrast between the natal sex and the gender identity of transgender people remains elusive. In recent years, techniques such as functional magnetic resonance imaging fMRI have begun to yield clues to possible biological underpinnings of the condition known as gender dysphoria. Techniques such as functional MRI have begun to yield clues to possible biological underpinnings of gender. The results may not have much effect on how gender dysphoria is diagnosed and treated, notes Baudewijntje Kreukels , who studies gender incongruence at VU University Medical Center in Amsterdam.

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Are the Brains of Transgender People Different from Those of Cisgender People?

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People who have intersex conditions have anatomy that is not considered typically male or female. Most people with intersex conditions come to medical attention because doctors or parents notice something unusual about their bodies. In contrast, people who are transgendered have an internal experience of gender identity that is different from most people. These are similarities. In spite of these similarities, these two groups should not be and cannot be thought of as one.
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LGBTQA Glossary of Terms

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This list will be updated as often as possible to keep up with the rapid proliferation of queer and trans language. The term cisgender is not indicative of gender expression, sexual orientation, hormonal makeup, physical anatomy, or how one is perceived in daily life. The term transgender is not indicative of gender expression, sexual orientation, hormonal makeup, physical anatomy, or how one is perceived in daily life. Also see: The Gender Unicorn. This term has a complicated history as a reclaimed slur.
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